| Company Name: |
Shanghai Macklin Biochemical Co.,Ltd.
|
| Tel: |
15221275939 |
| Email: |
shenlinxing@macklin.cn |
| Products Intro: |
Product Name:N-Acetylpuromycin
CAS:22852-13-7
Purity:98% Package:1mg；5mg
|
| Company Name: |
Shanghai Hongye Biotechnology Co. Ltd
|
| Tel: |
400-9205774 |
| Email: |
sales@glpbio.cn |
| Products Intro: |
Product Name:N-Acetylpuromycin
CAS:22852-13-7
Purity:>98% Package:1mg;10mg;50mg;100mg;
|
| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
|
| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:N-Acetylpuromycin
CAS:22852-13-7
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
|
N-Acetylpuromycin manufacturers
- N-Acetylpurinomycin
-
- $133.00 / 1mg
-
2026-04-13
- CAS:22852-13-7
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | N-Acetylpuromycin Basic information |
| Product Name: | N-Acetylpuromycin | | Synonyms: | N-Acetylpuromycin;3'-[[(2S)-2-(Acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyladenosine;Adenosine, 3'-[[(2S)-2-(acetylamino)-3-(4-methoxyphenyl)-1-oxopropyl]amino]-3'-deoxy-N,N-dimethyl-;3'-[(N-acetyl-O-methyl-L-tyrosyl)-amino]-N6,N6-dimethyl-3'-deoxy-adenosine | | CAS: | 22852-13-7 | | MF: | C24H31N7O6 | | MW: | 513.55 | | EINECS: | | | Product Categories: | | | Mol File: | 22852-13-7.mol |  |
| | N-Acetylpuromycin Chemical Properties |
| density | 1.47±0.1 g/cm3(Predicted) | | storage temp. | -20°C | | solubility | Soluble in DMSO (up to 70 mg/ml) or in DMF (up to 55 mg/ml) | | form | solid | | pka | 12.98±0.70(Predicted) | | color | White | | Stability: | Stable for 1 year from date of purchase as supplied. Solutions in DMSO or DMF may be stored at -20°C for up to 2 months. |
| | N-Acetylpuromycin Usage And Synthesis |
| Description | N-Acetylpuromycin is a non-ribotoxic form of the antibiotic puromycin that is formed in puromycin-resistant S. alboniger that endogenously express puromycin-acetyltransferase. In AD293(Pr) cells that express puromycin-N-acetyltransferase, the enzyme responsible for the biosynthesis of N-acetylpuromycin, puromycin application induces downregulation of the negative regulators of TGF-β signalling SnoN and Ski without activating MAPK or inhibition of protein synthesis. | | Uses | N-Acetylpurinomycin downregulates SnoN and Ski protein expression and promotes TGF-β signaling, independently of MAPK activation. | | storage | Store at -20°C | | References | [1] JACQUELINE HERNÁNDEZ-DAMIÁN . Downregulation of SnoN oncoprotein induced by antibiotics anisomycin and puromycin positively regulates transforming growth factor-β signals[J]. Biochimica et biophysica acta. General subjects, 2013, 1830 11: Pages 5049-5058. DOI:10.1016/j.bbagen.2013.07.006 |
| | N-Acetylpuromycin Preparation Products And Raw materials |
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