15(S)-FLUPROSTENOL

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15(S)-FLUPROSTENOL Basic information
Product Name:15(S)-FLUPROSTENOL
Synonyms:9ALPHA,11ALPHA,15S-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19,20-TETRANOR-PROSTA-5Z,13E-DIEN-1-OIC ACID;Travoprost Impurity 19(15(S)-Fluprostenol);5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, (5Z)-;TravoprostImpurity19-Fluprostenol);15(S)-FLUPROSTENOL
CAS:54276-24-3
MF:C23H29F3O6
MW:458.47
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Mol File:Mol File
15(S)-FLUPROSTENOL Structure
15(S)-FLUPROSTENOL Chemical Properties
Boiling point 608.0±55.0 °C(Predicted)
density 1.335±0.06 g/cm3(Predicted)
solubility DMF: 30 mg/ml; DMSO: 20 mg/ml; Ethanol: 30 mg/ml; PBS (pH 7.2): 5 mg/ml
pka4.76±0.10(Predicted)
Safety Information
MSDS Information
15(S)-FLUPROSTENOL Usage And Synthesis
Uses15(S)-Fluprostenol is the isomer of (+)-Fluprostenol (HY-108560). (+)-Fluprostenol is a potent agonist of PTGER2. (+)-Fluprostenol decreases the expression of Oviductal glycoprotein 1 (OVGP1)[1].
References[1] Zhang N, et al. The prostaglandin E2 receptor PTGER2 and prostaglandin F2α receptor PTGFR mediate oviductal glycoprotein 1 expression in bovine oviductal epithelial cells. J Reprod Dev. 2018;64(2):101-108. DOI:10.1262/jrd.2017-076
15(S)-FLUPROSTENOL Preparation Products And Raw materials
Tag:15(S)-FLUPROSTENOL(54276-24-3) Related Product Information
Tafluprost (Z)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-enyl]cyclopentyl]-N-(1,3-dihydroxypropan-2-yl)hept-5-enamide Fluprostenol (+)-Fluprostenol 2H-Cyclopenta[b]furan-2-one, hexahydro-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]-, (3aR,4R,5R,6aS)- 9-keto Fluprostenol isopropyl ester