SFTX-3.3

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SFTX-3.3 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
SFTX-3.3 Basic information
Product Name:SFTX-3.3
Synonyms:SFTX-3.3;Pentanamide, 2-amino-5-[(aminoiminomethyl)amino]-N-[3-[(3-aminopropyl)amino]propyl]-, (2S)-
CAS:141997-14-0
MF:C12H29N7O
MW:287.4
EINECS:
Product Categories:
Mol File:141997-14-0.mol
SFTX-3.3 Structure
SFTX-3.3 Chemical Properties
density 1.28±0.1 g/cm3(Predicted)
pka15.36±0.46(Predicted)
Safety Information
MSDS Information
SFTX-3.3 Usage And Synthesis
UsessFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels[1][2].
IC 50P/Q-type calciumchannel: 0.24 mM (IC50); N-type calcium channel: 0.70 mM (IC50)
References[1] Maria Elisa Calcagnotto, et al. An examination of calcium current function on heterotopic neurons in hippocampal slices from rats exposed to methylazoxymethanol. Epilepsia. 2003 Mar;44(3):315-21. DOI:10.1046/j.1528-1157.2003.41102.x
[2] T M Norris, et al. Block of high-threshold calcium channels by the synthetic polyamines sFTX-3.3 and FTX-3.3. Mol Pharmacol. 1996 Oct;50(4):939-46. PMID:8863840
[3] M Fatehi, et al. Polyamine FTX-3.3 and polyamine amide sFTX-3.3 inhibit presynaptic calcium currents and acetylcholine release at mouse motor nerve terminals. Neuropharmacology. 1997 Feb;36(2):185-94. DOI:10.1016/s0028-3908(96)00146-3
SFTX-3.3 Preparation Products And Raw materials
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