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| | Adenosine 5′-diphosphate sodium salt Basic information |
| | Adenosine 5′-diphosphate sodium salt Chemical Properties |
| Melting point | >174°C (dec.) | | Boiling point | 877.7° | | Fp | 484.6° | | storage temp. | -20°C | | solubility | Aquoues Base (Slightly), Methanol (Slightly), Water (Slightly) | | form | Solid | | color | White to Off-White | | biological source | bacterial | | Water Solubility | water: 50mg/mL | | Stability: | Hygroscopic | | InChIKey | NAZRYZKZIIRXMG-JHVGCDEENA-N | | SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(=O)OP(O)(O)=O)O[C@H]1N1C=NC2C(=NC=NC1=2)N)O.[NaH] |&1:1,2,3,15,r| | | CAS DataBase Reference | 20398-34-9(CAS DataBase Reference) |
| | Adenosine 5′-diphosphate sodium salt Usage And Synthesis |
| Description | Adenosine 5′-diphosphate sodium salt (ADP-NA) is an adenine nucleotide phosphorylated into ATP by ATPase. This phosphorylation is a crucial part of cellular homeostatis as it allows energy storage and is involved in nucleic acid metabolism. | | Uses | Adenosine 5'-diphosphate sodium salt (ADP-NA) is a nucleoside diphosphate, which is the product of ATP dephosphorylation by ATPases. Adenosine 5'-diphosphate sodium salt induces human platelet aggregation and inhibits stimulated adenylate cyclase by an action at P2T-purinoceptors[1][2][3]. | | Biological Functions | Adenosine 5′-diphosphate sodium salt (ADP-NA) affects platelet activation through its interaction with ADP receptors P2Y1, P2Y12 and P2X1. Upon its conversion to adenosine by ecto-ADPases, platelet activation is inhibited via adenosine receptors. | | IC 50 | Human Endogenous Metabolite | | References | [1] Arts IC, et al. Adenosine 5'-triphosphate (ATP) supplements are not orally bioavailable: a randomized, placebo-controlled cross-over trial in healthy humans. J Int Soc Sports Nutr. 2012 Apr 17;9(1):16. DOI:10.1186/1550-2783-9-16
[2] Noel J. Cusack, et al. Effects of phosphate-modified analogs of adenosine 5′-diphosphate and adenosine 5′‐triphosphate at P2T-purinoceptors mediating human platelet activation by ADP. April 1996.
[3] Adenosine-5'-diphosphate |
| | Adenosine 5′-diphosphate sodium salt Preparation Products And Raw materials |
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