MCH-1 antagonist 1

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MCH-1 antagonist 1 manufacturers
MCH-1 antagonist 1 Basic information
Product Name:MCH-1 antagonist 1
Synonyms:MCH-1 antagonist 1;2(1H)-Pyridinone, 4-(phenylmethoxy)-1-[1-[2-(1-pyrrolidinyl)ethyl]-1H-indazol-5-yl]-;MCH1 antagonist 1,MCH 1 antagonist 1
CAS:1039825-68-7
MF:C25H26N4O2
MW:414.5
EINECS:
Product Categories:
Mol File:1039825-68-7.mol
MCH-1 antagonist 1 Structure
MCH-1 antagonist 1 Chemical Properties
storage temp. Store at -20°C
solubility Soluble in DMSO
Safety Information
MSDS Information
MCH-1 antagonist 1 Usage And Synthesis
UsesMCH-1 Antagonist 1, is a potent melanin concentrating hormone (MCH-1) antagonist.
in vivo

MCH-1 antagonist 1 is administered to male C57BL/6J DIO mice to assess their pharmacokinetic profile. Effect of MCH-1 antagonist 1 (dosed at 30 mg/kg, po) is measured on the body weight of DIO mice with the AUC0-6 h of 14760 h*ng/mL[1].

IC 50MCH-1: 2.6 nM (Ki); CYP3A4: 10 μM (IC50)
MCH-1 antagonist 1 Preparation Products And Raw materials
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