Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2

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Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 Basic information
Product Name:Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2
Synonyms:Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2;DNP-P-CHA-ABU-CYS(ME)-HA-K(NMA)-NH2;MATRIX METALLOPROTEINASE-1 FLUOROGENIC SUBSTRATE III;MMP-1 FLUOROGENIC SUBSTRATE III;Matrix Metalloproteinase-1 Fluorogenic Substrate III;MMP-1 Fluorogenic Substrate III
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MW:0
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Mol File:Mol File
Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 Structure
Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 Chemical Properties
solubility Formic Acid: 1 mg/ml
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MSDS Information
Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 Usage And Synthesis
Description

Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 is a fluorogenic substrate for matrix metalloproteinase-1 (MMP-1) and MMP-9. It is cleaved by MMP-1 and MMP-9 to release N-methylanthranilic acid (Nma), which is unquenched and its fluorescence can be used to quantify MMP activity.

References[1] BICKETT D.M. A High Throughput Fluorogenic Substrate for Interstitial Collagenase (MMP-1) and Gelatinase (MMP-9)[J]. Analytical biochemistry, 1993, 212 1: Pages 58-64. DOI: 10.1006/abio.1993.1291
SequeneDnp-Pro-Cha-Abu-Cys(Me)-His-Ala-Lys(Nma)-NH2
Dnp-P-Cha-Abu-Cys(Me)-HA-K(Nma)-NH2 Preparation Products And Raw materials
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