(D-TRP2,7,9)-SUBSTANCE P manufacturers
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| | (D-TRP2,7,9)-SUBSTANCE P Basic information |
| Product Name: | (D-TRP2,7,9)-SUBSTANCE P | | Synonyms: | (D-TRP2,7,9)-SUBSTANCE P;H-ARG-D-TRP-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2;ARG-D-TRP-LYS-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-MET-NH2;L-Methioninamide, L-arginyl-D-tryptophyl-L-lysyl-L-prolyl-L-glutaminyl-L-glutaminyl-D-tryptophyl-L-phenylalanyl-D-tryptophyl-L-leucyl- (9CI) | | CAS: | 100930-11-8 | | MF: | C80H109N21O13S | | MW: | 1604.92 | | EINECS: | | | Product Categories: | | | Mol File: | 100930-11-8.mol |  |
| | (D-TRP2,7,9)-SUBSTANCE P Chemical Properties |
| density | 1.44±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 13.27±0.46(Predicted) |
| | (D-TRP2,7,9)-SUBSTANCE P Usage And Synthesis |
| Uses | [D-Trp2,7,9] Substance P is a tachykinin (Neurokinin Receptor) antagonist with Ki values of 1 μM, 1.3 μM, and ~9 μM for NK-1, NK-2,and NK-3 receptor, respectively[1]. | | IC 50 | NK1: 1 μM (Ki); NK2: 1.3 μM (Ki); NK3: ~9 μM (Ki) | | References | [1] S H Buck, et al. Agonist and antagonist binding to tachykinin peptide NK-2 receptors. Life Sci. 1988;42(26):2701-8. DOI:10.1016/0024-3205(88)90246-9 |
| | (D-TRP2,7,9)-SUBSTANCE P Preparation Products And Raw materials |
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