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| Product Name: | TBP antibody | | Synonyms: | TBP antibody;Mouse Monoclonal TBP Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![TBP antibody Structure]() |
| | TBP antibody Chemical Properties |
| | TBP antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | TATA-binding protein is a ubiquitously expressed nuclear protein that functions at the core of the general transcription factor protein complex TFIID. TFIID, which contains TBP and 13 TBP-associated factors, contributes to the formation of the transcription pre-initiation complex, an assembly of multiple protein complexes that bind to a gene promoter during the initiation of transcription. Once the pre-initiation complex is formed, RNA polymerase II becomes competent for elongation and transcribes the body of a gene. TBP functions in the recruitment of TFIID by binding to the TATA-box sequence found approximately 25 base pairs upstream of the transcription start site of many protein-coding genes. In addition, many transcriptional activator proteins interact with TBP and various TAF proteins to facilitate recruitment of TFIID and formation of the pre-initiation complex. | | References | [1] Goodrich, J.A. and Tjian, R. (1994) Curr Opin Cell Biol 6, 403-9.
[2] Berk, A.J. (2000) Cell 103, 5-8.
[3] Thomas, M.C. and Chiang, C.M. (2006) Crit Rev Biochem Mol Biol 41, 105-78. |
| | TBP antibody Preparation Products And Raw materials |
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