| Company Name: |
Shanghai Universal Biotech Co.,Ltd
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| Tel: |
15921930842 15921930842 |
| Email: |
yh-wang@univ-bio.com |
| Products Intro: |
Product Name:Dvl2 Antibody
Package:100ul Remarks: 见优宁维官网
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| Company Name: |
Hubei Ipodix Biotechnology Co.,Ltd.
|
| Tel: |
18007124176 19384116026 |
| Email: |
2706668885@qq.com |
| Products Intro: |
Product Name:DVL2 antibody
Purity:99% Package:50ul/RMB 1280;100ul/RMB 2180
|
| Company Name: |
CUSABIO TECHNOLOGY LLC
|
| Tel: |
027-87196173 |
| Email: |
cusabio@163.com |
| Products Intro: |
Product Name:DVL2 Antibody
|
| Company Name: |
Shanghai Qierqi Biotech Co., Ltd.
|
| Tel: |
027-19371278702 18008634902 |
| Email: |
ruihening88@163.com |
| Products Intro: |
Product Name:Rabbit Polyclonal DVL2 Antibody
Package:20μl;50μl;100μl
|
| Company Name: |
Enzo Biochem Inc
|
| Tel: |
Enzo Biochem Inc. 13797054060 |
| Email: |
Enzoname@qq.com |
| Products Intro: |
Product Name:DVL2 Antibody
|
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| Product Name: | DVL2 antibody | | Synonyms: | DVL2 antibody;Rabbit Polyclonal DVL2 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![DVL2 antibody Structure]() |
| | DVL2 antibody Chemical Properties |
| | DVL2 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Hamster;Monkey;Mink | | Background | Dishevelled proteins are important intermediates of Wnt signaling pathways. Dsh inhibits glycogen synthase kinase-3β promoting β-catenin stabilization. Dsh proteins also participate in the planar cell polarity pathway by acting through JNK. There are three Dsh homologs, Dvl1, Dvl2 and Dvl3 in mammals. Upon treatment with Wnt proteins, Dvls become hyperphosphorylated and accumulate in the nucleus. Dvl proteins also associate with actin fibers and cytoplasmic vesicular membranes and mediate endocytosis of the Fzd receptor after Wnt protein stimulation. Overexpression of Dvl has been reported in certain cancers. | | References | [1] Logan, C.Y. and Nusse, R. (2004) Annu. Rev. Cell Dev. Biol. 20, 781-810.
[2] Boutros, M. and Mlodzik, M. (1999) Mech. Dev. 83, 27-37.
[3] Lee, J.S. et al. (1999) J. Biol. Chem. 274, 21464-70.
[4] Itoh, K. et al. (2005) J. Biol. 4, 3.1-3.12.
[5] Capelluto, D.G. et al. (2002) Nature 419, 726-729.
[6] Chen, W. et al. (2003) Science 301, 1391-1394.
[7] Okino , K. et al. (2003) Oncol. Rep. 10, 1219-1223.
[8] Uematsu, K. et al. (2003) Oncogene 22, 7218-7221. |
| | DVL2 antibody Preparation Products And Raw materials |
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