| Company Name: |
Fedprotein |
| Tel: |
13041401126; 13041401126 |
| Email: |
3690410801@qq.com |
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| Product Name: | GCK antibody | | Synonyms: | GCK antibody;Rabbit Polyclonal GCK Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![GCK antibody Structure]() |
| | GCK antibody Chemical Properties |
| | GCK antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse;Rat;Monkey | | Background | Germinal center kinase is the founding member of the GCK family, a group of serine/threonine kinases homologous to the yeast Ste20 kinase. GCK is activated by TNF and associated with TRAF2 and MEKK1, thereby activating the SAPK/JNK pathway. GCK does not significantly phosphorylate MEKK1, instead it enhances MEKK1 oligomerization and autophosphorylation. GCK binds and activates MLK3, indicating that GCK may have other effectors. | | References | [1] Pombo, C. M. et al. (1995) Nature 377, 750-754.
[2] Yuasa, T. et al. (1998) J. Biol. Chem. 273, 22681-22692.
[3] Chadee, D. N. et al. (2002) Mol. Cell. Biol. 22, 737-749. |
| | GCK antibody Preparation Products And Raw materials |
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