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| Product Name: | GSTM1 antibody | | Synonyms: | GSTM1 antibody;Mouse Monoclonal GSTM1 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![GSTM1 antibody Structure]() |
| | GSTM1 antibody Chemical Properties |
| | GSTM1 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Mouse;Rat | | Background | Glutathione S-transferase Mu 1, encoded by GSTM1, belongs to the superfamily of glutathione-S transferases. It is a phase 2 enzyme involved in the inactivation of reactive oxygen species and metabolism of xenobiotics, using glutathione and generating oxidized glutathione. Polymorphisms of the gene have been associated with nasopharyngeal cancer, laryngeal cancer, colorectal cancer, hypertension, and chronic kidney disease. In the brain, GSTM1 contributes to astrocyte-mediated enhancement of microglia activation during brain inflammation as it is required for nuclear factor κB activation and proinflammatory mediator production. | | References | [1] Levy, R. and Le, T.H. (2022) Kidney 360 3, 2153-2163.
[2] Zhang, F. et al. (2017) Onco Targets Ther 10, 1433-1440.
[3] Song, L. et al. (2020) Biosci Rep 40, BSR20201927. doi: 10.1042/BSR20201927.
[4] Kano, S.I. et al. (2019) Sci Signal 12, eaar2124. doi: 10.1126/scisignal.aar2124. |
| | GSTM1 antibody Preparation Products And Raw materials |
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