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| Product Name: | TRPV3 antibody | | Synonyms: | TRPV3 antibody;Rabbit Polyclonal TRPV3 Antibody | | CAS: | | | MF: | | | MW: | 0 | | EINECS: | | | Product Categories: | | | Mol File: | Mol File | ![TRPV3 antibody Structure]() |
| | TRPV3 antibody Chemical Properties |
| | TRPV3 antibody Usage And Synthesis |
| Source | Rabbit | | Reactivity | Human;Mouse | | Background | The transient receptor potential cation channel subfamily V member 3 is a widely expressed ligand-gated ion channel protein that acts in temperature detection between 22º C and 40º C. Related transient receptor proteins respond to different temperature ranges; TRPA1 responds to cold temperatures and TRPM1 to cool, while warmer temperatures elicit response from TRPV3 and TRPV4. Noxious heat or painful temperatures correlate with TRPM8 and TRPV1 activity. TRPV3 is found in association with TRPV1 and is thought to modulate activity of this noxious heat-responsive protein. Increased TRPV1 and TRPV3 protein expression is correlated with nervous injury, while reduced expression of both may be see in cases of diabetic skin neuropathy. Recent evidence implicates TRPV3 in pruritic dermatitis, or itching associated with eczema and related skin disorders. | | References | [1] Xu, H. et al. (2002) Nature 418, 181-6.
[2] Facer, P. et al. (2007) BMC Neurol 7, 11.
[3] Smith, G.D. et al. (2002) Nature 418, 186-90.
[4] Steinhoff, M. and Bíró, T. (2009) J Invest Dermatol 129, 531-5. |
| | TRPV3 antibody Preparation Products And Raw materials |
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