STAT5-IN-2 manufacturers
- STAT5-IN-2
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2026-08-12
- CAS:2111834-61-6
- Min. Order: 1KG
- Purity: 98%
- Supply Ability: 1000kg
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| | STAT5-IN-2 Basic information |
| Product Name: | STAT5-IN-2 | | Synonyms: | STAT5-IN-2;STAT5 inhibitor 17f;Quinoline, 1,2,3,4-tetrahydro-1-[2-(1H-indol-5-yloxy)ethyl]-4,4-dimethyl-6-(3-pyridinyl)-;STAT-5-IN-2,STAT5IN2,STAT5 IN 2;1-(2-((1H-Indol-5-yl)oxy)ethyl)-4,4-dimethyl-6-(pyridin-3-yl)-1,2,3,4-tetrahydroquinoline;STAT5-IN-2, 10 mM in DMSO;STAT5-IN-2 ，E2398 | | CAS: | 2111834-61-6 | | MF: | C26H27N3O | | MW: | 397.51 | | EINECS: | | | Product Categories: | | | Mol File: | 2111834-61-6.mol |  |
| | STAT5-IN-2 Chemical Properties |
| Boiling point | 635.5±55.0 °C(Predicted) | | density | 1.160±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | solubility | DMSO : 100 mg/mL (251.57 mM; Need ultrasonic) | | pka | 16.56±0.30(Predicted) | | form | Solid | | color | Off-white to light yellow |
| | STAT5-IN-2 Usage And Synthesis |
| Uses | STAT5-IN-2 is a STAT5 inhibitor, extracted from reference 1, example 17f. STAT5-IN-2 has potent antileukemic effect[1]. | | IC 50 | STAT5: 9 μM (EC50, in K562 cells); STAT5: 5 μM (EC50, in KU812 cells ) | | References | [1] Ludovic Juen, et al. New Inhibitor Targeting Signal Transducer and Activator of Transcription 5 (STAT5) Signaling in Myeloid Leukemias. J Med Chem. 2017 Jul 27;60(14):6119-6136. DOI:10.1021/acs.jmedchem.7b00369 |
| | STAT5-IN-2 Preparation Products And Raw materials |
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