N-(DBCO-PEG4)-N-Biotin-PEG4-NHS

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Products Intro: Product Name:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
CAS:2353409-72-8
Purity:98.00% Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
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Products Intro: Product Name:N-(DBCO-PEG4)-N-biotin-PEG4-NHS
CAS:2353409-72-8
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Products Intro: Product Name:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
CAS:2353409-72-8
Purity:95%+ Package:1g;5g;10g;25g;50g;100g; Remarks:accept Custom Synthesis Services, support large packing
Company Name: Xian confluore Biological Technology Co., Ltd.
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Products Intro: Product Name:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
CAS:2353409-72-8
Purity:>95.00% Package:10mg
Company Name: Xi'an Confluore Biological Technology Co., Ltd.  
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Products Intro: Product Name:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
CAS:2353409-72-8
Purity:>99.00% Package:25mg;50mg;100mg

N-(DBCO-PEG4)-N-Biotin-PEG4-NHS manufacturers
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS Basic information
Product Name:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS
Synonyms:N-(DBCO-PEG4)-N-Biotin-PEG4-NHS;4,7,10,13,19,22,25,28-Octaoxa-16,31-diazapentatriacontanoic acid, 35-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-16-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-32,35-dioxo-, 2,5-dioxo-1-pyrrolidinyl ester;2,5-Dioxo-1-pyrrolidinyl 35-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-16-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]-32,35-dioxo-4,7,10,13,19,22,25,28-octaoxa-16,31-diazapentatriacontanoate
CAS:2353409-72-8
MF:C54H74N6O16S
MW:1095.26
EINECS:
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Mol File:2353409-72-8.mol
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS Structure
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS Chemical Properties
density 1.33±0.1 g/cm3(Predicted)
solubility Soluble in Water, DCM, DMF
pka13.90±0.40(Predicted)
Safety Information
MSDS Information
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS Usage And Synthesis
DescriptionN-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry biotinylation reagent, NHS active esters can be used to label the primary amines (-NH2) of proteins and other amine-attached macromolecule. DBCO group is very reactive with azide molecule via copper-free Click Chemistry.
UsesN-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(DBCO-PEG4)-N-Biotin-PEG4-NHS is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
IC 50PEGs
References[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(DBCO-PEG4)-N-Biotin-PEG4-NHS Preparation Products And Raw materials
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