3-Propylpyridine

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Company Name: HBCChem, Inc.  
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3-Propylpyridine manufacturers

  • 3-propylpyridine
  • 3-propylpyridine pictures
  • $1.00
  • 2026-08-07
  • CAS:4673-31-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 100000KG
3-Propylpyridine Basic information
Product Name:3-Propylpyridine
Synonyms:1-(3-Pyridyl)propane;3-propyl-pyridin;Pyridine, 5-propyl;3-N-PROPYL PYRIDINE;Pyridine, 3-propyl-;Einecs 225-122-3;3-Propylpyridine
CAS:4673-31-8
MF:C8H11N
MW:121.18
EINECS:225-122-3
Product Categories:
Mol File:4673-31-8.mol
3-Propylpyridine Structure
3-Propylpyridine Chemical Properties
Melting point 163 °C
Boiling point 75-77 °C(Press: 16 Torr)
density 0.9264 g/cm3
storage temp. Inert atmosphere,Room Temperature
pka5.56±0.10(Predicted)
Odorat 0.10 % in propylene glycol. sweet musty beany earthy woody
AppearanceColorless to light yellow Liquid
Odor Typebeany
LogP2.359 (est)
EPA Substance Registry System3-Propylpyridine (4673-31-8)
Safety Information
TSCA TSCA listed
MSDS Information
3-Propylpyridine Usage And Synthesis
Synthesis
Iodoethane

75-03-6

3-PROPYLPYRIDINE

4673-31-8

The general procedure for the synthesis of 3-propylpyridine from ethyl iodide was as follows: i) n-butyllithium (BuLi, 1.6 M hexane solution, 15.4 mL, 25 mmol) was added drop-wise to a tetrahydrofuran (THF, 35 mL) solution of diisopropylamine (3.53 mL, 24.7 mmol) at 0 °C. After 30 min, hexamethylphosphorotriamine (HMPA , 15.7 g, 24.7 mmol) was added and the mixture was kept at 0 °C for 15 min. Subsequently, a THF (10 mL) solution of 3-methylpyridine (2.3 g, 24.7 mmol) was added dropwise.After 30 min, a THF (10 mL) solution of ethyl iodide (EtI, 3.45 g, 24.7 mmol) was added dropwise.The reaction mixture was stirred for 1 h at room temperature. After completion of the reaction, the mixture was poured into 10% hydrochloric acid (HCl) solution. The aqueous phase was extracted with ether (Et2O), the organic phase was washed with water, dried over anhydrous sodium sulfate and concentrated under vacuum to give a yellow oily product (300 mg, 10% yield), which could be used in subsequent steps without further purification.

References[1] Patent: WO2007/71358, 2007, A1. Location in patent: Page/Page column 32-33
3-Propylpyridine Preparation Products And Raw materials
Raw materialsIodoethane-->Hexamethylphosphoramide-->Tetrahydrofuran-->Diisopropylamine-->n-Butyllithium-->petroleum ether 40 60
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