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| | 2-AMINO-3-METHOXYBENZOIC ACID Basic information |
| | 2-AMINO-3-METHOXYBENZOIC ACID Chemical Properties |
| Melting point | 169-170 °C (lit.) | | Boiling point | 333.9±27.0 °C(Predicted) | | density | 1.303±0.06 g/cm3(Predicted) | | storage temp. | Keep in dark place,Sealed in dry,Room Temperature | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.82±0.10(Predicted) | | form | Powder | | color | White to yellow to brown | | Major Application | peptide synthesis | | InChI | InChI=1S/C8H9NO3/c1-12-6-4-2-3-5(7(6)9)8(10)11/h2-4H,9H2,1H3,(H,10,11) | | InChIKey | SXOPCLUOUFQBJV-UHFFFAOYSA-N | | SMILES | C(O)(=O)C1=CC=CC(OC)=C1N | | CAS DataBase Reference | 3177-80-8(CAS DataBase Reference) |
| Hazard Codes | Xi | | Risk Statements | 36/37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 3 | | HS Code | 29225090 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| | 2-AMINO-3-METHOXYBENZOIC ACID Usage And Synthesis |
| Chemical Properties | White to light brown crystals or powder | | Uses | 2-Amino-3-methoxybenzoic Acid is used in the preparation of CDK1/cyclin B inhibitors for application towards antitumor treatment. In addition, it is used in the synthesis of Alogliptin, an inhibitor o
f dipeptidy peptidase, which aids in the lowering of blood-glucose for potential treatment of diabetes. | | Definition | ChEBI: 3-methoxyanthranilic acid is an aminobenzoic acid that is anthranilic acid in which the hydrogen at position 3 is substituted by a methoxy group. It is a metabolite of kynurenine. It has a role as a mammalian metabolite. It is a member of benzoic acids and an aminobenzoic acid. It is functionally related to an anthranilic acid. It is a conjugate acid of a 3-methoxyanthranilate. | | Synthesis Reference(s) | The Journal of Organic Chemistry, 63, p. 6797, 1998 DOI: 10.1021/jo972158g | | reaction suitability | reaction type: solution phase peptide synthesis |
| | 2-AMINO-3-METHOXYBENZOIC ACID Preparation Products And Raw materials |
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