1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE

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1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Basic information
Product Name:1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE
Synonyms:1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE;4-hydroxy-3-hydroxymethylacetophenone;Ethanone, 1-[4-hydroxy-3-(hydroxymethyl)phenyl]-;Salbutamol Impurity 50;2-(3-formyl-2-hydroxyphenyl)acetic acid;1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHA;Ibandronate Impurity 28;1-(4-Hydroxy-3-(hydroxymethyl)phenyl)ethanone - [H93389]
CAS:39235-58-0
MF:C9H10O3
MW:166.17
EINECS:
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Mol File:Mol File
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Structure
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Chemical Properties
Melting point 121 °C
Boiling point 381.4±32.0 °C(Predicted)
density 1.247±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Acetone, Chloroform
form Solid
pka8.13±0.18(Predicted)
color Off-White
Safety Information
MSDS Information
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Usage And Synthesis
Uses1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone is an intermediate in synthesizing Albuterol Dimer Ether (A514520), which is an impurity of Albuterol (Salbutamol) (A514500). Albuterol impurity F. Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic.
PreparationObtained by refluxing 3-chloromethyl-4-hydroxy-acetophenone with water for 3 h (70%).
1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE Preparation Products And Raw materials
Preparation Products1-(3-CHLOROMETHYL-4-HYDROXY-PHENYL)-ETHANONE-->4-Acetoxy-3-acetoxymethylacetophenone
Tag:1-[4-HYDROXY-3-(HYDROXYMETHYL)PHENYL]ETHANONE(39235-58-0) Related Product Information

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