4-NITROPHENYLACETYLENE

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CAS:937-31-5
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CAS:937-31-5
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  • 2025-12-01
  • CAS:937-31-5
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  • 2022-02-22
  • CAS:937-31-5
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  • 4-NITROPHENYLACETYLENE
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  • CAS:937-31-5
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4-NITROPHENYLACETYLENE Basic information
Product Name:4-NITROPHENYLACETYLENE
Synonyms:(4-Nitrophenyl)ethyne;(p-Nitrophenyl)acetylene;1-Nitro-4-ethynylbenzene;4-Ethynyl-1-nitrobenzene;4-Ethynylnitrobenzene;4-Nitroethynylbenzene;NSC 71089;p-Ethynylnitrobenzene
CAS:937-31-5
MF:C8H5NO2
MW:147.13
EINECS:
Product Categories:Miscellaneous;Aromatics Compounds;Aromatics;Alkynes;Organic Building Blocks;Terminal;pharmacetical;Intermediates
Mol File:937-31-5.mol
4-NITROPHENYLACETYLENE Structure
4-NITROPHENYLACETYLENE Chemical Properties
Melting point 148-150 °C(lit.)
Boiling point 246.6±23.0 °C(Predicted)
density 1.22±0.1 g/cm3(Predicted)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Ethanol, Ether
form Solid
color Light Yellow
λmax286nm(CH2Cl2)(lit.)
InChIInChI=1S/C8H5NO2/c1-2-7-3-5-8(6-4-7)9(10)11/h1,3-6H
InChIKeyGAZZTEJDUGESGQ-UHFFFAOYSA-N
SMILESC1(C#C)=CC=C([N+]([O-])=O)C=C1
CAS DataBase Reference937-31-5(CAS DataBase Reference)
Safety Information
Safety Statements 24/25
WGK Germany 3
HS Code 29049090
Storage Class11 - Combustible Solids
MSDS Information
ProviderLanguage
SigmaAldrich English
4-NITROPHENYLACETYLENE Usage And Synthesis
Chemical PropertiesLight Yellow Solid
Uses4-Nitrophenylacetylene (cas# 937-31-5) is a compound useful in organic synthesis.
Synthesis Reference(s)Tetrahedron, 62, p. 6673, 2006 DOI: 10.1016/j.tet.2005.12.077
Synthesis4-Nitrophenylacetylene is synthesized in two steps. Step 1: 1-Iodo-4-nitrobenzene and (trimethylsilyl)acetylene react in DMF at 50C in the presence of Pd(PPh3)2Cl2, CuI, and Et3N to yield [4-(nitrophenyl)ethynyl]trimethylsilane. Step 2: This silyl derivative is treated with TBAF in THF at 0C. After quenching, extraction and purification give 4-nitrophenylacetylene.
4-NITROPHENYLACETYLENE Preparation Products And Raw materials
Preparation ProductsP-NITROPHENYL PHOSPHATE
Tag:4-NITROPHENYLACETYLENE(937-31-5) Related Product Information
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