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| | PEG3-C4-OBn Basic information |
| Product Name: | PEG3-C4-OBn | | Synonyms: | PEG3-C4-OBn;Ethanol, 2-[2-[[6-(phenylmethoxy)hexyl]oxy]ethoxy]-;2-(2-((6-(Benzyloxy)hexyl)oxy)ethoxy)ethan-1-ol | | CAS: | 2381196-79-6 | | MF: | C17H28O4 | | MW: | 296.4 | | EINECS: | | | Product Categories: | | | Mol File: | 2381196-79-6.mol |  |
| | PEG3-C4-OBn Chemical Properties |
| Boiling point | 413.5±35.0 °C(Predicted) | | density | 1.031±0.06 g/cm3(Predicted) | | solubility | Soluble in DMSO | | pka | 14.37±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | PEG3-C4-OBn Usage And Synthesis |
| Uses | PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1 (HY-125878). PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2]. | | Biological Activity | PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. PEG3-C4-OBn can be used in the synthesis of the PROTAC SGK3 degrader-1. PROTAC SGK3 degrader-1 is a potent SKG3 degrader based on PROTAC[1][2]. | | IC 50 | PEGs | | References | [1]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 5.
[2]. Tovell H, et al. Design and Characterization of SGK3-PROTAC1, an Isoform Specific SGK3 Kinase PROTAC Degrader. ACS Chem Biol. 2019 Sep 20;14(9):2024-2034. |
| | PEG3-C4-OBn Preparation Products And Raw materials |
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