Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-

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Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Suppliers list
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Products Intro: Product Name:JAB-3068
CAS:2169223-48-5
Purity:99.6% Package:1mg;55USD|5mg;129USD|10mg;198USD
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Products Intro: Product Name:SHP2-IN-6
CAS:2169223-48-5
Purity:98% HPLC Package:100mg，500mg，1g，5g，10g
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Products Intro: Product Name:JAB-3068
CAS:2169223-48-5
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Products Intro: CAS:2169223-48-5
Purity:98%
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Products Intro: Product Name:JAB-3068
CAS:2169223-48-5
Purity:99% Package:1mg;5mg;10mg

Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- manufacturers

  • JAB-3068
  • JAB-3068 pictures
  • $55.00
  • 2026-05-11
  • CAS:2169223-48-5
  • Purity: 99.78%
  • Supply Ability: 10g
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Basic information
Product Name:Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-
Synonyms:Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-;(S)-1-(4-((3-amino-5-(4-amino-2-oxa-8-azaspiro[4.5]decan-8-yl)pyrazin-2-yl)thio)-3,3-difluoroindolin-1-yl)ethan-1-one;SHP2-IN-6;HMN23485;JAB3068
CAS:2169223-48-5
MF:C22H26F2N6O2S
MW:476.54
EINECS:
Product Categories:
Mol File:2169223-48-5.mol
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Structure
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Chemical Properties
Boiling point 732.6±60.0 °C(Predicted)
density 1.48±0.1 g/cm3(Predicted)
pka9.26±0.20(Predicted)
form Solid
color Off-white to light yellow
Safety Information
MSDS Information
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Usage And Synthesis
UsesJAB-3068 (SHP2-IN-6) is a potent SHP2 inhibitor, extracted from patent WO2017211303A1, compound 7, has an IC50 of 25.8 nM[1].
References[1] Cunbo Ma, et al. Novel heterocyclic derivatives useful as shp2 inhibitors. WO2017211303A1.
Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]- Preparation Products And Raw materials
Tag:Ethanone, 1-[4-[[3-amino-5-[(4S)-4-amino-2-oxa-8-azaspiro[4.5]dec-8-yl]-2-pyrazinyl]thio]-3,3-difluoro-2,3-dihydro-1H-indol-1-yl]-(2169223-48-5) Related Product Information