β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl

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β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Darexaban glucuronide；YM-222714;YM 222714;YM222714
CAS:432029-12-4
Package:100 mg；500 mg Remarks:REAGENT;FOR LABORATORY USE ONLY
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354
Email: marketing@targetmol.com
Products Intro: Product Name:Darexaban glucuronide
CAS:432029-12-4
Package:100mg;2500USD|50mg;1980USD|25mg;1520USD
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:Darexaban glucuronide
CAS:432029-12-4
Package:100mg/RMB 17500;50mg/RMB 13800;25mg/RMB 10600

β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl manufacturers
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Basic information
Product Name:β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl
Synonyms:β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl;Darexaban glucuronide;YM 222714;YM222714;YM-222714
CAS:432029-12-4
MF:C33H38N4O10
MW:650.69
EINECS:
Product Categories:
Mol File:432029-12-4.mol
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Structure
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Chemical Properties
Boiling point 778.9±60.0 °C(Predicted)
density 1.436±0.06 g/cm3(Predicted)
pka2.77±0.70(Predicted)
Safety Information
MSDS Information
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Usage And Synthesis
DescriptionDarexaban glucuronide, also known as YM-222714, is the major component in plasma after oral administration of darexaban to humans and is the pharmacologically active metabolite. Darexaban (YM150) is a direct inhibitor of factor Xa. It is an experimental drug that acts as an anticoagulant and antithrombotic to prevent venous thromboembolism after a major orthopaedic surgery, stroke in patients with atrial fibrillation and possibly ischemic events in acute coronary syndrome. It is used in form of the maleate. The development of darexaban was discontinued in September 2011.
UsesDarexaban glucuronide (YM-222714) is a active metabolite of darexaban (YM150). Darexaban glucuronide has an oral activity and antithrombotic effect[1].
References[1] "Yoshiyuki Iwatsuki, et al. Biochemical and pharmacological profile of darexaban, an oral direct factor Xa inhibitor. Eur J Pharmacol. 2011 Dec 30;673(1-3):49-55. ." DOI:10.1016/j.ejphar.2011.10.009
β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl Preparation Products And Raw materials
Tag:β-D-Glucopyranosiduronic acid, 2-[[4-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)benzoyl]amino]-3-[(4-methoxybenzoyl)amino]phenyl(432029-12-4) Related Product Information