1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]-

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1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Suppliers list
Company Name: Jinan Carbotang Biotech Co.,Ltd.
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Products Intro: Product Name:1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]-
CAS:1287766-55-5
Purity:98% Package:5KG;1KG
Company Name: TargetMol Chemicals Inc.
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Email: marketing@targetmol.com
Products Intro: Product Name:Tigulixostat
CAS:1287766-55-5
Purity:98.07% Package:1mg;117USD|5mg;289USD|10mg;463USD
Company Name: ANHUI CHICO CHEMICAL CO., LTD.
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Products Intro: Product Name:1H-Pyrazole-4 carboxylic acid, 1-[3 cyano-1-(1-methylethyl)-1H-indol-5-yl]-
CAS:1287766-55-5
Purity:99.0% Package:100KG;25KG;1KG;
Company Name: Zhuhai Kerui Biotechnology Co., Ltd  Gold
Tel: 18990613995
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Products Intro: Product Name:TIGULIXOSTAT
CAS:1287766-55-5
Purity:99% Package:5kg;10kg
Company Name: WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.  
Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Products Intro: Product Name:Tigulixostat ; LC-350189 ; LC350189 ; LC 350189
CAS:1287766-55-5
Purity:98.0% Package:50.0mg 100.0mg 200.0mg 500.0mg 1.0g

1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- manufacturers

  • Tigulixostat
  • Tigulixostat pictures
  • $100.00
  • 2026-07-15
  • CAS:1287766-55-5
  • Purity: 99.97%
  • Supply Ability: 10g
1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Basic information
Product Name:1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]-
Synonyms:1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]-;LC 350189;LC-350189;TigTigulixostat;LC350189;Tigulixostat
CAS:1287766-55-5
MF:C16H14N4O2
MW:294.31
EINECS:
Product Categories:
Mol File:1287766-55-5.mol
1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Structure
1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Chemical Properties
Boiling point 554.5±35.0 °C(Predicted)
density 1.33±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
form Solid
pka3.70±0.10(Predicted)
color White to light yellow
Safety Information
MSDS Information
1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Usage And Synthesis
UsesTigulixostat (LC350189) is an orally active, non-purine selective xanthine oxidase inhibitor. Tigulixostat lowers the production of uric acid. Tigulixostat can be used for gout and hyperuricemia study[1][2][3].
References[1] Seonghae Yoon, et al. Pharmacokinetics, pharmacodynamics, and tolerability of LC350189, a novel xanthine oxidase inhibitor, in healthy subjects. Drug Des Devel Ther. 2015 Aug 31;9:5033-49. DOI:10.2147/DDDT.S86884
[2] Li X, et al. Pharmacological urate-lowering approaches in chronic kidney disease. Eur J Med Chem. 2019 Mar 15;166:186-196. DOI:10.1016/j.ejmech.2019.01.043
[3] Terkeltaub R, et al. Serum Urate-Lowering Efficacy and Safety of Tigulixostat in Gout Patients With Hyperuricemia: A Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Trial. Arthritis Rheumatol. 2023 Jul;75(7):1275-1284. DOI:10.1002/art.42447
1H-Pyrazole-4-carboxylic acid, 1-[3-cyano-1-(1-methylethyl)-1H-indol-5-yl]- Preparation Products And Raw materials
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