- Sodium picosulfate
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- $0.00 / 25Kg/Drum
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2026-02-13
- CAS:10040-45-6
- Min. Order: 1KG
- Purity: 98.5%-100.5%; BP
- Supply Ability: 500KGS
- Sodium Picosulfate
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- $44.00 / 50mg
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2026-01-31
- CAS:10040-45-6
- Min. Order:
- Purity: 99.71%
- Supply Ability: 10g
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| | Sodium picosulfate Basic information |
| | Sodium picosulfate Chemical Properties |
| Melting point | 283-286°C | | storage temp. | Keep in dark place,Inert atmosphere,Room temperature | | solubility | Freely soluble in water, slightly soluble in ethanol 96 per cent. | | form | Solid | | color | White to Off-White | | Stability: | Hygroscopic | | Major Application | pharmaceutical
pharmaceutical small molecule | | InChI | InChI=1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2 | | InChI | 1S/C18H15NO8S2.2Na/c20-28(21,22)26-15-8-4-13(5-9-15)18(17-3-1-2-12-19-17)14-6-10-16(11-7-14)27-29(23,24)25;;/h1-12,18H,(H,20,21,22)(H,23,24,25);;/q;2*+1/p-2 | | InChIKey | GOZDTZWAMGHLDY-UHFFFAOYSA-L | | SMILES | C(C1N=CC=CC=1)(C1=CC=C(OS([O-])(=O)=O)C=C1)C1C=CC(OS([O-])(=O)=O)=CC=1.[Na+].[Na+] |
| WGK Germany | WGK 3 | | HS Code | 2933399090 | | Storage Class | 11 - Combustible Solids | | Toxicity | mouse,LD50,intraperitoneal,2900mg/kg (2900mg/kg),LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATIONBEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD,Iyakuhin Kenkyu. Study of Medical Supplies. Vol. 8, Pg. 341, 1977. |
| | Sodium picosulfate Usage And Synthesis |
| Chemical Properties | Off-White Solid | | Originator | Guttalax, De Angelini, Italy ,1967 | | Uses | Sodium picosulfate acts as a stimulant laxative by increasing the frequency and the force of peristalsis and promoting electrolyte and water retention in the colon. Sodium picosulfate is most often used as laxatives. | | Uses | Sodium picosulfate is a stimulant laxative related to bis-acedyl; used for the treatment of constipation and for evaluation of the colon by stimulation bowel movements following hydrolysis by colon bacteria. | | Definition | ChEBI: Sodium picosulfate is an aryl sulfate and a member of pyridines. | | Therapeutic Function | Laxative | | Side effects |
Major minor side effects for Sodium Picosulfate:Diarrhoea, Abdominal pain, Nausea and vomiting, and Stomach cramps.
| | Synthesis | The general procedure for the synthesis of (pyridin-2-ylmethylene)bis(4,1-phenylene)bis(sodium sulfate salt) from 4,4'-(pyridin-2-ylmethylene)bisphenol was as follows: the crude product of 4,4'-(pyridin-2-ylmethylene)bisphenol was dissolved in pyridine, and 39.5 g of chlorosulphonic acid was added slowly dropwise over the temperature range from 0 to 10°C. The reaction was carried out with continuous stirring. After the dropwise addition, the temperature was gradually increased to the reaction temperature and the reaction was continuously stirred for 1 hour. Subsequently, the reaction mixture was allowed to stir naturally at room temperature for 4 hours. Upon completion of the reaction, the reaction mixture was slowly poured into ice water and the pH was adjusted to 10 with 6 M sodium hydroxide solution. extraction was carried out with dichloromethane and the aqueous phase was separated and concentrated under reduced pressure. Finally, the product was collected by filtration and dried under vacuum at 40 °C to afford 34.8 g of sodium 4,4'-(pyridin-2-ylmethylene)diphenylsulfite, the product was a white solid with 99.8% purity and 86.4% yield. | | References | [1] Patent: CN105175317, 2017, B. Location in patent: Paragraph 0054-0055; 0060 |
| | Sodium picosulfate Preparation Products And Raw materials |
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