- GS-2989
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- $1.00 / 1g
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2025-02-13
- CAS:2013-58-3
- Min. Order: 1g
- Purity: 0.98
- Supply Ability: 1000
- Meclocycline
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- $0.00 / 1Kg
-
2020-05-25
- CAS:2013-58-3
- Min. Order: 1KG
- Purity: 99.0%+
- Supply Ability: 300 MT
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| | meclocycline Basic information |
| Product Name: | meclocycline | | Synonyms: | meclocycline;Meclocycline base;MECLOCYLINE;Chlormethylenecycline;(4S)-4β-(Dimethylamino)-1,4,4aβ,5,5aβ,6,11,12a-octahydro-3,5β,10,12,12aβ-pentahydroxy-6-methylene-7-chloro-1,11-dioxo-2-naphthacenecarboxamide;(4S,4aR,5S,5aR,12aS)-7-Chloro-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxo-2-naphthacenecarboxamide;GS-2989;NSC-78502 | | CAS: | 2013-58-3 | | MF: | C22H21ClN2O8 | | MW: | 476.86 | | EINECS: | 217-938-3 | | Product Categories: | | | Mol File: | 2013-58-3.mol |  |
| | meclocycline Chemical Properties |
| Melting point | >167°C (dec.) | | Boiling point | 837.0±65.0 °C(Predicted) | | density | 1.72±0.1 g/cm3(Predicted) | | storage temp. | Amber Vial, -20°C Freezer, Under inert atmosphere | | solubility | DMSO (Slightly), Methanol (Slightly) | | pka | 4.50±1.00(Predicted) | | form | Solid | | color | Yellow to Dark Yellow | | Stability: | Light Sensitive |
| Toxicity | LD50 in mice (mg/kg): >5000 orally, 425 i.p. (Bernardi) |
| | meclocycline Usage And Synthesis |
| Uses | Meclocycline is a semi-synthetic tetracycline prepared by dehydration of the 6-hydroxy group of chlortetracycline to yield an exocyclic 6-methylene. Meclocyline is a close structural analogue of methacycline. Like all tetracyclines, meclocycline shows broad spectrum antibacterial and antiprotozoan activity and acts by binding to the 30S and 50S ribosomal sub-units, blocking protein synthesis. Meclocycline has been extensively cited in the literature with over 400 references. | | Uses | Meclocycline is a close structural analogue of methacycline which shows antibacterial and antiprotozoan activity. | | Definition | ChEBI: Meclocycline is a member of tetracyclines. | | Brand name | Meclan (Johnson & Johnson). | | IC 50 | Tetracycline |
| | meclocycline Preparation Products And Raw materials |
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