o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1)

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o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) manufacturers
o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) Basic information
Product Name:o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1)
Synonyms:o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1);Cloperastine Febdizoate;1-[2-[(4-Chlorophenyl)phenylmethoxy]ethyl]piperidine Fendizoate;Levocloperastine Fendizoate Racemic Impurity;1-[2-[(4-chlorophenyl)-phenylmethoxy]ethyl]piperidine,2-(4-hydroxy-3-phenylbenzoyl)benzoic acid;Cloperastine fendiz;o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) ISO 9001：2015 REACH;o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, co...
CAS:85187-37-7
MF:C40H38ClNO5
MW:648.2
EINECS:286-126-9
Product Categories:
Mol File:85187-37-7.mol
o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) Structure
o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) Chemical Properties
Melting point 185-187°C
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
color White to Off-White
Stability:Hygroscopic
InChIKeyPXZFKAKWSHBDCP-UHFFFAOYSA-N
SMILESC(C1C=CC=CC=1)(C1C=CC(Cl)=CC=1)OCCN1CCCCC1.OC1=CC=C(C(C2C=CC=CC=2C(=O)O)=O)C=C1C1C=CC=CC=1
Safety Information
MSDS Information
o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) Usage And Synthesis
UsesCloperastine fendizoate is used in the treatment of chronic non-productive cough. Antitussive. it is the salt of Cloperastine (CAS:3703-76-2)
DefinitionChEBI: Cloperastine fendizoate is a N-oxyethylpiperidine. It is functionally related to a benzoate.
in vivo

In the anesthetized guinea pigs, Cloperastine at a therapeutic dose of 1 mg/kg prolonged the QT interval and monophasic action potential (MAP) duration without affecting PR interval or QRS width[1]. Cloperastine hydrochloride shows relatively low acute toxicity when administered by the intraperitoneal route in rats and mice, and shows minor toxicity by the oral route when administered as Cloperastine fendizoate, the LD50 in rats and mice for the two administration routes exceeds 1000 and 2000 mg/kg, respectively[2].

o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1) Preparation Products And Raw materials
Tag:o-[(2'-hydroxy[1,1'-biphenyl]-4-yl)carbonyl]benzoic acid, compound with 1-[2-(4-chlorobenzhydryloxy)ethyl]piperidine (1:1)(85187-37-7) Related Product Information
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