Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- manufacturers
- AGG-523
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- $2190.00
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2026-05-21
- CAS:920289-29-8
- Purity:
- Supply Ability: 10g
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| | Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- Basic information |
| | Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- Chemical Properties |
| Boiling point | 756.4±60.0 °C(Predicted) | | density | 1.212±0.06 g/cm3(Predicted) | | pka | 4.47±0.10(Predicted) |
| | Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- Usage And Synthesis |
| Uses | AGG-523 (PF-5212371) is a reversible, non-hydroxamate, zinc-binding selective aggrecanase 1 (ADAMTS4) and aggrecanase 2 (ADAMTS5) inhibitor. AGG-523 can be used for the study of osteoarthritis (OA)[1]. | | References | [1] Wang K, et al. Investigational drugs for the treatment of osteoarthritis. Expert Opin Investig Drugs. 2015;24(12):1539-56. DOI:10.1517/13543784.2015.1091880 |
| | Pentanoic acid, 4-[([1,1'-biphenyl]-4-ylcarbonyl)amino]-5-[[2-(4-fluorophenyl)-1,1-dimethylethyl]amino]-5-oxo-, (4S)- Preparation Products And Raw materials |
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