- Broad Bean Extract
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2026-06-01
- CAS:152-93-2
- Min. Order: 1kg
- Purity: HPLC
- Supply Ability: 20 t
- Vicine
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- $51.00
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2026-04-20
- CAS:152-93-2
- Purity: 99.82%
- Supply Ability: 10g
- VICINE
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2025-12-24
- CAS:152-93-2
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 1000KG
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| | 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Basic information |
| | 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Chemical Properties |
| Melting point | 242-244℃ | | alpha | D26 -11.7° (c = 3.9 in 0.2N NaOH) | | Boiling point | 445.09°C (rough estimate) | | density | 2.18 | | refractive index | 1.6200 (estimate) | | solubility | Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) | | pka | 9.56±0.50(Predicted) | | form | Solid | | color | White to off-white | | BRN | 44407 | | Stability: | Hygroscopic | | InChI | 1S/C10H16N4O7/c11-7-6(8(19)14-10(12)13-7)21-9-5(18)4(17)3(16)2(1-15)20-9/h2-5,9,15-18H,1H2,(H5,11,12,13,14,19)/t2-,3-,4+,5-,9+/m1/s1 | | InChIKey | KGNGTSCIQCLKEH-SYCVNHKBSA-N | | SMILES | O[C@@H]1[C@@H](O)[C@H](OC2=C(N)NC(N)=NC2=O)O[C@H](CO)[C@H]1O |
| WGK Germany | 3 | | Storage Class | 11 - Combustible Solids | | Hazard Classifications | Acute Tox. 4 Oral |
| | 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Usage And Synthesis |
| Uses | Vicine is a pyrimidine glycosides, a precursor of the aglycons divicine and isouramil which is main factors of favism. It is found in faba/fava bean. Also, it is derived from Ethyl Glyoxylate (E918550), which is used as a reagent in the synthesis of a new class of cinnamyl-triazole compounds which can be used as selective inhibitors of human aromatase (cytochrome P 450 19A1) | | Definition | ChEBI: Vicine is a glycoside. | | in vivo | "High levels" of Vicine might have shortened the birds' survival time by enhancing the neurotoxicity induced by "lower levels" of BCA[1].
| | Purification Methods | Crystallise Vicine from water (1%) or aqueous 85% EtOH, and dry it at 135o. [Bendich & Clements Biochim Biophys Acta 12 462 1953, Beilstein 31 H 163, 2 5 III/IV 4285.] |
| | 2,6-diamino-5-(beta-D-glucopyranosyloxy)-(1H)-pyrimidin-4-one Preparation Products And Raw materials |
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