| Company Name: |
Energy Chemical |
| Tel: |
400-0056266 |
| Email: |
marketing1@energy-chemical.com |
| Company Name: |
TargetMol |
| Tel: |
400-821-0310 15002144251 |
| Email: |
xuexiang.shao@tsbiochem.com |
|
| | BAY R3401 Basic information |
| Product Name: | BAY R3401 | | Synonyms: | 4-(2-Chlorophenyl)-1-ethyl-2-methyl-5-oxo-1,4,5,7-tetrahydrofuro[3,4-b]pyridine-3-carboxylic acid isopropyl ester;BAY R3401 >=98% (HPLC), solid;Furo[3,4-b]pyridine-3-carboxylic acid, 4-(2-chlorophenyl)-1-ethyl-1,4,5,7-tetrahydro-2-methyl-5-oxo-, 1-methylethyl ester | | CAS: | 100276-03-7 | | MF: | C20H22ClNO4 | | MW: | 375.85 | | EINECS: | | | Product Categories: | | | Mol File: | 100276-03-7.mol |  |
| | BAY R3401 Chemical Properties |
| Melting point | 110-112 °C | | Boiling point | 512.6±50.0 °C(Predicted) | | density | 1.28±0.1 g/cm3(Predicted) | | storage temp. | 2-8°C | | solubility | DMSO: soluble15mg/mL | | form | solid | | pka | -0.68±0.70(Predicted) | | color | white |
| Hazard Codes | Xn | | Risk Statements | 22 | | WGK Germany | 3 |
| | BAY R3401 Usage And Synthesis |
| Uses | BAY R3401 is an orally active glycogen phosphorylase inhibitor that can achieve irreversible and non-selective inhibition of hepatic glycogenolysis. BAY R3401 inhibits glycogenolysis in liver cells, with IC50 values of 27.06 and 52.83 μM in HL-7702 and HepG2 cells, respectively. BAY R3401 can be used for the research of type 2 diabetes[1]. | | References | [1] Zhang L, et al. Design, Synthesis, and Biological Application of Novel Photoaffinity Probes of Dihydropyridine Derivatives, BAY R3401. Molecules. 2019 Jun 28;24(13):2394. DOI:10.3390/molecules24132394 |
| | BAY R3401 Preparation Products And Raw materials |
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