1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1)

1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Suppliers list
Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
Tel: 15076683720
Email: klq@cw-bio.com
Products Intro: Product Name:1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1)
CAS:212141-52-1
Purity:大于96% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only.
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Products Intro: Product Name:Vatalanib hydrochloride
CAS:212141-52-1
Purity:99.70% Package:10mg/RMB 3690;50mg/RMB 8250
Company Name: Shanghai Amole Biotechnology Co., Ltd.  
Tel: 18916360931 18916360931
Email: 2596183085@qq.com
Products Intro: Product Name:Vatalanib hydrochloride
CAS:212141-52-1
Purity:5mg;50mg;25mg;200mg;1mg;10mg;100mg Package:99%
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Basic information
Product Name:1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1)
Synonyms:1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1)
CAS:212141-52-1
MF:C20H16Cl2N4
MW:383.28
EINECS:
Product Categories:
Mol File:212141-52-1.mol
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Structure
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Chemical Properties
Safety Information
MSDS Information
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Usage And Synthesis
UsesVatalanib (PTK787; ZK-222584; CGP-797870) hydrochloride is an inhibitor of VEGFR2/KDR with an IC50 of 37 nM[1].
References[1] Wood JM, et al. PTK787/ZK 222584, a novel and potent inhibitor of vascular endothelial growth factor receptor tyrosine kinases, impairs vascular endothelial growth factor-induced responses and tumor growth after oral administration. Cancer Res. 2000;60(8):2178-2189. PMID:10786682
[2] Wan J, et al. Local recurrence of small cell lung cancer following radiofrequency ablation is induced by HIF-1α expression in the transition zone. Oncol Rep. 2016;35(3):1297-1308. DOI:10.3892/or.2015.4541
[3] Murakami M, et al. Tyrosine kinase inhibitor PTK/ZK enhances the antitumor effects of interferon-α/5-fluorouracil therapy for hepatocellular carcinoma cells. Ann Surg Oncol. 2011;18(2):589-596. DOI:10.1245/s10434-010-1310-y
1-Phthalazinamine, N-(4-chlorophenyl)-4-(4-pyridinylmethyl)-, hydrochloride (1:1) Preparation Products And Raw materials
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