| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:2-(3,7-Dimethyl-5-oxo-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-6-yl)-N-(5-(2-fluorobenzyl)thiazol-2-yl)acetamide
CAS:1214561-09-7
Purity:98% Package:1mg;5mg Remarks:BD01459653
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| Company Name: |
Shanghai Merlot Chemical Co., LTD
|
| Tel: |
15821661757 |
| Email: |
226174156@qq.com |
| Products Intro: |
Product Name:HPK1-IN-8
CAS:1214561-09-7
Purity:95% Package:1g；5g
|
| Company Name: |
TargetMol Chemicals Inc.
|
| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:HPK1-IN-8
CAS:1214561-09-7
Package:10mg/RMB 8787
|
1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- manufacturers
- HPK1-IN-8
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- $1255.00 / 10mg
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2025-12-16
- CAS:1214561-09-7
- Min. Order:
- Purity: 99.68%
- Supply Ability: 10g
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| | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Basic information |
| Product Name: | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- | | Synonyms: | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo-;HPK1-IN-8;2-(3,7-Dimethyl-5-oxo-1,5-dihydro-[1,2,4]triazolo[4,3-a]pyrimidin-6-yl)-N-(5-(2-fluorobenzyl)thiazol-2-yl)acetamide | | CAS: | 1214561-09-7 | | MF: | C19H17FN6O2S | | MW: | 412.44 | | EINECS: | | | Product Categories: | | | Mol File: | 1214561-09-7.mol | ![1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Structure](CAS/20210305/GIF/1214561-09-7.gif) |
| | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Chemical Properties |
| density | 1.53±0.1 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 8.27±0.50(Predicted) | | form | Solid | | color | White to off-white |
| | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Usage And Synthesis |
| Uses | HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1. | | Biological Activity | HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1. | | References | [1]. Wang W, et al. Discovery of an Allosteric, Inactive Conformation-Selective Inhibitor of Full-Length HPK1 Utilizing a Kinase Cascade Assay. Biochemistry. 2021 Oct 19;60(41):3114-3124. |
| | 1,2,4-Triazolo[4,3-a]pyrimidine-6-acetamide, N-[5-[(2-fluorophenyl)methyl]-2-thiazolyl]-1,5-dihydro-3,7-dimethyl-5-oxo- Preparation Products And Raw materials |
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