Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]-

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Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Suppliers list
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Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- manufacturers

  • GV150013
  • GV150013 pictures
  • $197.00
  • 2026-05-06
  • CAS:167355-22-8
  • Purity: 99.93%
  • Supply Ability: 10g
Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Basic information
Product Name:Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]-
Synonyms:Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]-;GV 150013;GV150013;GV-150013;(R)-1-(1-(adamantan-1-ylmethyl)-2,4-dioxo-5-phenyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepin-3-yl)-3-phenylurea;GV150013, 10 mM in DMSO
CAS:167355-22-8
MF:C33H34N4O3
MW:534.65
EINECS:
Product Categories:
Mol File:167355-22-8.mol
Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Structure
Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Chemical Properties
Boiling point 792.3±60.0 °C(Predicted)
density 1.34±0.1 g/cm3(Predicted)
pka9.56±0.20(Predicted)
Safety Information
MSDS Information
Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Usage And Synthesis
UsesGV-150013 is a selective CCK-B receptor antagonist. GV-150013 has sleep aid effect[1].
DefinitionChEBI: GV 150013X is a benzodiazepine.
in vivo

GV-150013 (0.5 - 60μg/kg, ip, Once) increase REM sleep and non-REM sleep in old rats model[1].

Animal Model:Old rats [2].
Dosage:0.5 μg/kg, 5μg/kg, 60μg/kg
Administration:Intraperitoneal injection, Once
Result:The duration of REM sleep and non-REM sleep was longer than that of control.
References[1] Crespi F. Cholecystokinin-B (CCK-B) receptor antagonists improve "aged" sleep: a new class of sleep modulators Methods Find Exp Clin Pharmacol. 1999 Jan-Feb;21(1):31-8. DOI:10.1358/mf.1999.21.1.527016
[2] F.Crespi, et al. Influence of cholecystokinin-B (CCK-B) receptor antagonists on rat electroencephalography (EEG): A new class of sleep modulators Gaviraghi. Dept of Pharmacology GlaxoWellcome S.p.A., Medicine Research Centre, via A. Fleming, 4, 37135 Verona, Italy
Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]- Preparation Products And Raw materials
Tag:Urea, N-phenyl-N'-[(3R)-2,3,4,5-tetrahydro-2,4-dioxo-1-phenyl-5-(tricyclo[3.3.1.13,7]dec-1-ylmethyl)-1H-1,5-benzodiazepin-3-yl]-(167355-22-8) Related Product Information
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