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| | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH Basic information |
| Product Name: | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH | | Synonyms: | Myelin Basic Protein (83-99) (bovine)
MBP (83-99) (bovine);MBP (83-99) (bovine);MYELIN BASIC PROTEIN (83-99) (BOVINE);8:PN:US20130183327 SEQID:9 claimed sequence;L-Proline, L-α-glutamyl-L-asparaginyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-phenylalanyl-L-phenylalanyl-L-lysyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-;H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH | | CAS: | 178823-45-5 | | MF: | C93H143N25O24 | | MW: | 1995.28 | | EINECS: | | | Product Categories: | | | Mol File: | 178823-45-5.mol |  |
| | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH Chemical Properties |
| density | 1.46±0.1 g/cm3(Predicted) | | storage temp. | -15°C | | pka | 3.39±0.20(Predicted) | | Sequence | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH |
| | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH Usage And Synthesis |
| Uses | MBP (83-99) is a MBP-specific T cell lines recognizing the immunodominant epitope. MBP (83-99) induces proliferation and IFN-γ secreting of T cells[1][2]. | | in vivo | MBP(83-99) (50 μg; subcutaneous injection; once) generates weak IFN-γ secreting T cells in immunize SJL/J mice[2]. | | References | [1] Hemmer B, et al. Human T-cell response to myelin basic protein peptide (83-99): extensive heterogeneity in antigen recognition, function, and phenotype. Neurology. DOI:10.1212/wnl.49.4.1116
[2] Katsara M, et al. A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89. DOI:10.1016/j.jneuroim.2008.06.013 |
| | H-Glu-Asn-Pro-Val-Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro-OH Preparation Products And Raw materials |
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