Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]-

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Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]- Basic information
Product Name:Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]-
Synonyms:Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]-;WAY-299727;N-(4-(2-((4-Oxo-3,4-dihydroquinazolin-2-yl)thio)acetyl)phenyl)acetamide;HDAC2-IN-2
CAS:332169-78-5
MF:C18H15N3O3S
MW:353.39
EINECS:
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Mol File:332169-78-5.mol
Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]- Structure
Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]- Chemical Properties
density 1.37±0.1 g/cm3(Predicted)
pka14.46±0.70(Predicted)
form Solid
color White to off-white
Safety Information
MSDS Information
Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]- Usage And Synthesis
UsesHDAC2-IN-2 (compound 124) is an inhibitor of HDAC2 with Kd value of 0.1-1 μM[1].
References[1] Preparation of inhibitors of histone deacetylase. World Intellectual Property Organization, WO2015200619 A1 2015-12-30.
Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]- Preparation Products And Raw materials
Tag:Acetamide, N-[4-[2-[(3,4-dihydro-4-oxo-2-quinazolinyl)thio]acetyl]phenyl]-(332169-78-5) Related Product Information
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