4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester

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4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: Guangdong Wengjiang Chemical Reagent Co.,Ltd.  
Tel: 0751-2815983 13927872582
Email: 3008325437@qq.com
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester manufacturers

  • PQQ-TME
  • PQQ-TME pictures
  • $1980.00
  • 2026-05-11
  • CAS:74447-88-4
  • Purity:
  • Supply Ability: 10g
4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Basic information
Product Name:4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester
Synonyms:4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester;4,5-Dioxo-4,5-dihydro-1H-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester;1H-Pyrrolo(2,3-F)quinoline-2,7,9-tricarboxylic acid, 4,5-dihydro-4,5-dioxo-, trimethyl ester;Coenzyme pqq trimethyl ester;Methoxatin trimethyl ester;Pqq trimethyl ester;Trimethyl 4,5-dihydro-4,5-dioxo-1H-pyrrolo(2,3-F)quinoline-2,7,9-tricarboxylate;PQQ-TME
CAS:74447-88-4
MF:C17H12N2O8
MW:372.28578
EINECS:
Product Categories:
Mol File:74447-88-4.mol
4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Structure
4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Chemical Properties
form Solid
color Orange to red
Safety Information
MSDS Information
4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Usage And Synthesis
UsesPQQ-trimethylester (PQQ-TME) is a synthetic compound that is a trimethylester derivative of pyrroloquinoline quinone (PQQ). PQQ-trimethylester has twice the blood-brain barrier permeability of PQQ (HY-100196) in vitro. In addition, PQQ-trimethylester shows strong inhibitory activity against α-synuclein, amyloid β1-42 (Aβ1-42) and prion protein fibrillation. PQQ-trimethylester can be used in the study of neurodegenerative diseases[1].
IC 50α-synuclein Aggregation
References[1] Tsukakoshi K, et al. Esterification of PQQ enhances blood-brain barrier permeability and inhibitory activity against amyloidogenic protein fibril formation[J]. ACS Chemical Neuroscience, 2018, 9(12): 2898-2903. DOI:10.1021/acschemneuro.8b00355
4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester Preparation Products And Raw materials
Preparation ProductsPyrroloquinoline quinone
Tag:4,5-Dioxo-4,5-dihydro-1H-pyrrol[2,3-f]quinoline-2,7,9-tricarboxylic acid trimethyl ester(74447-88-4) Related Product Information
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