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| | 5-Chloro-2-nitropyridine Basic information |
| | 5-Chloro-2-nitropyridine Chemical Properties |
| Melting point | 119-123℃ | | Boiling point | 275.3±20.0 °C(Predicted) | | density | 1.489±0.06 g/cm3(Predicted) | | storage temp. | Inert atmosphere,Room Temperature | | form | crystalline powder | | pka | -4.87±0.22(Predicted) | | color | White to very faint yellow | | InChI | InChI=1S/C5H3ClN2O2/c6-4-1-2-5(7-3-4)8(9)10/h1-3H | | InChIKey | YUBHMOQVHOODEI-UHFFFAOYSA-N | | SMILES | C1([N+]([O-])=O)=NC=C(Cl)C=C1 | | CAS DataBase Reference | 52092-47-4(CAS DataBase Reference) |
| Hazard Codes | Xi,N,Xn | | Risk Statements | 20/21/22-36/37/38-50-41-22 | | Safety Statements | 26-36/37/39-36-61-37/39 | | RIDADR | UN 2811 6.1/PG 3 | | WGK Germany | 2 | | Hazard Note | Irritant | | HazardClass | 6.1 | | HS Code | 2933399990 | | Storage Class | 6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects | | Hazard Classifications | Acute Tox. 4 Oral
Aquatic Acute 1
Eye Dam. 1
Skin Irrit. 2
STOT SE 3 |
| | 5-Chloro-2-nitropyridine Usage And Synthesis |
| Uses | 5-Chloro-2-nitropyridine can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process. | | Synthesis | 
To concentrated H2SO4 (50 ml) was added 30 % H2O2 (25mL) at 0 C and a solution of 5-chloropyridin-2-amine (5.0 g, 39 mmol) in concentrated H2SO4 (20 mL) was added at 0 C. The mixture was stirred for 20 hours at room temperature. The mixture was poured into ice water under vigorously stirring and the resulting solid was filtered. The solid was recrystallized from ethanol to give 5-chloro-2-nitropyridine. 5-chloro-2-nitropyridine. MS m/z 159 (M+ 1)+. | | References | [1] Patent: US6849647, 2005, B1. Location in patent: Page/Page column 145
[2] Yakugaku Zasshi, 1952, vol. 72, p. 381
[3] Chem.Abstr., 1953, p. 6403
[4] Zhurnal Obshchei Khimii, 1940, vol. 10, p. 1105
[5] Chem. Zentralbl., 1940, vol. 111, # II, p. 3474 |
| | 5-Chloro-2-nitropyridine Preparation Products And Raw materials |
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