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| | Amanozine Basic information |
| Product Name: | Amanozine | | Synonyms: | Amanozine;2-Amino-4-anilino-s-triazine;N-Phenyl-1,3,5-triazine-2,4-diamine;(4-amino-s-triazin-2-yl)-phenyl-amine;2-N-phenyl-1,3,5-triazine-2,4-diamine;Amanozina;Amanozinum;Amenozin | | CAS: | 537-17-7 | | MF: | C9H9N5 | | MW: | 187.2 | | EINECS: | | | Product Categories: | | | Mol File: | 537-17-7.mol |  |
| | Amanozine Chemical Properties |
| Melting point | 235-236° | | Boiling point | 311.95°C (rough estimate) | | density | 1.2986 (rough estimate) | | refractive index | 1.6900 (estimate) | | pka | 3.79±0.10(Predicted) |
| | Amanozine Usage And Synthesis |
| Originator | Amanozine,Onbio Inc. | | Definition | ChEBI: Amanozine is a diamino-1,3,5-triazine. | | Manufacturing Process | 21.3 g (0.1 mole) of 1-phenylbiguanide hydrochloride were dissolved in hot
water and the solution was added to 5.3 g (0.05 mole) sodium carbonate by
stirring. On cooling 15 g of the needle crystals have fallen. They were heated
to reflux with 80 ml of dry formic acid. Then 40-50 ml formic acid was distilled
off. The residue was with water diluted, cooled with ice and the conc. alkali
was added. The precipitate fallen. It was filtered off and recrystallized from
40-50% ethanol. The pure product 4-amino-2-anilino-1,3,5-triazine had MP:
232°-233°C.
Monochlorohydrate of it crystallized as long colorless needles melted at 258°-
260°C. | | Therapeutic Function | Diuretic | | Purification Methods | It crystallises from dioxane or 50% aqueous EtOH. [Beilstein 26 III/IV 1195.] |
| | Amanozine Preparation Products And Raw materials |
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