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13348960310 13348960310 |
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Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]- manufacturers
- TRPM4-IN-2
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2026-07-18
- CAS:667411-04-3
- Purity: 99.21%
- Supply Ability: 10g
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| | Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]- Basic information |
| | Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]- Chemical Properties |
| Boiling point | 631.9±55.0 °C(Predicted) | | density | 1.425±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 3.00±0.10(Predicted) | | form | Solid | | color | White to off-white |
| | Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]- Usage And Synthesis |
| Uses | TRPM4-IN-2 (NBA) is a potent transient receptor potential melastatin 4 (TRPM4) inhibitor with an IC50 value of 0.16 μM. TRPM4-IN-2 can be used for researching prostate cancer and colorectal cancer[1][2]. | | IC 50 | TRPM4: 0.16 μM (IC50) | | References | [1] Borgstrm A, et al. Small Molecular Inhibitors Block TRPM4 Currents in Prostate Cancer Cells, with Limited Impact on Cancer Hallmark Functions. J Mol Biol. 2021 Aug 20;433(17):166665. DOI:10.1016/j.jmb.2020.09.024
[2] Stokosa P, et al. Investigation of Novel Small Molecular TRPM4 Inhibitors in Colorectal Cancer Cells. Cancers (Basel). 2021 Oct 28;13(21):5400. DOI:10.3390/cancers13215400 |
| | Benzoic acid, 4-chloro-2-[[2-(1-naphthalenyloxy)acetyl]amino]- Preparation Products And Raw materials |
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