Methanesulfonamide, N-[3-[2-[[4-(1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-7-yl]phenyl]- manufacturers
- FLT3-IN-17
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- $1990.00
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2026-07-27
- CAS:2758999-62-9
- Purity:
- Supply Ability: 10g
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| | Methanesulfonamide, N-[3-[2-[[4-(1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-7-yl]phenyl]- Basic information |
| | Methanesulfonamide, N-[3-[2-[[4-(1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-7-yl]phenyl]- Chemical Properties |
| Boiling point | 756.6±70.0 °C(Predicted) | | density | 1.415±0.06 g/cm3(Predicted) | | pka | 7.85±0.10(Predicted) | | form | Solid | | color | Light yellow to yellow |
| | Methanesulfonamide, N-[3-[2-[[4-(1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-7-yl]phenyl]- Usage And Synthesis |
| Uses | FLT3-IN-17 inhibits CYPs and FLT3 mutants activity (IC50s: <0.5 nM for D835Y). FLT3-IN-17 is also a FAK inhibitor, with an IC50 value of 12 nM. FLT3 ligand-2 can be used in the research of cancers[1]. | | References | [1] Hanna Cho, et al. Identification of Thieno[3,2- d]pyrimidine Derivatives as Dual Inhibitors of Focal Adhesion Kinase and FMS-like Tyrosine Kinase 3. J Med Chem. 2021 Aug 26;64(16):11934-11957. DOI:10.1021/acs.jmedchem.1c00459 |
| | Methanesulfonamide, N-[3-[2-[[4-(1-piperazinyl)phenyl]amino]thieno[3,2-d]pyrimidin-7-yl]phenyl]- Preparation Products And Raw materials |
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