Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)-

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Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- manufacturers
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- Basic information
Product Name:Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)-
Synonyms:Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)-;Aldose reductase-IN-4
CAS:2446136-17-8
MF:C14H10FNO3S
MW:291.3
EINECS:
Product Categories:
Mol File:2446136-17-8.mol
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- Structure
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- Chemical Properties
Boiling point 498.5±55.0 °C(Predicted)
density 1.42±0.1 g/cm3(Predicted)
pka5.99±0.20(Predicted)
Safety Information
MSDS Information
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- Usage And Synthesis
UsesAldose reductase-IN-4 (compund IIc) is an aldose reductase inhibitor with IC50s of 11.70 μM and 0.98 μM for aldehyde reductase 1 (ALR1) and ALR2, respectively[1].
References[1] Konstantinos Koutsopoulos, et al. Design synthesis and evaluation of novel aldose reductase inhibitors: The case of indolyl-sulfonyl-phenols. Bioorg Med Chem. 2020 Aug 1;28(15):115575. DOI:10.1016/j.bmc.2020.115575
Phenol, 2-fluoro-4-(1H-indol-1-ylsulfonyl)- Preparation Products And Raw materials
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