| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:FUBP1-IN-2
CAS:1242862-71-0
Package:50mg/RMB 13800;25mg/RMB 10600;100mg/RMB 17500
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Benzoic acid, 5-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-[(4-methoxybenzoyl)amino]- manufacturers
- FUBP1-IN-2
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- $1980.00 / 50mg
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2025-10-27
- CAS:1242862-71-0
- Min. Order:
- Purity:
- Supply Ability: 10g
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| | Benzoic acid, 5-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-[(4-methoxybenzoyl)amino]- Basic information |
| | Benzoic acid, 5-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-[(4-methoxybenzoyl)amino]- Chemical Properties |
| Boiling point | 649.0±55.0 °C(Predicted) | | density | 1.331±0.06 g/cm3(Predicted) | | pka | 3.72±0.36(Predicted) |
| | Benzoic acid, 5-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-[(4-methoxybenzoyl)amino]- Usage And Synthesis |
| Uses | FUBP1-IN-2 (compound 9) is a potent FUBP1 (far upstream binding protein 1) inhibitor. FUBP1-IN-2 inhibits the KH4 FUBP1-FUSE interaction in a gel shift assay. FUBP1-IN-2 binds to FUBP1 in a ChIP assay. FUBP1-IN-2 reduces both c-Myc mRNA and protein expression, increases p21 mRNA and protein expression, and depletes intracellular polyamines[1]. | | References | [1] Dobrovolskaite A, et al. Discovery of Anthranilic Acid Derivatives as Difluoromethylornithine Adjunct Agents That Inhibit Far Upstream Element Binding Protein 1 (FUBP1) Function. J Med Chem. 2022 Nov 24;65(22):15391-15415. DOI:10.1021/acs.jmedchem.2c01350 |
| | Benzoic acid, 5-[4-(5-chloro-2-methylphenyl)-1-piperazinyl]-2-[(4-methoxybenzoyl)amino]- Preparation Products And Raw materials |
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