4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)-

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Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- manufacturers
4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- Basic information
Product Name:4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)-
Synonyms:4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)-;Antituberculosis agent-2
CAS:2411741-01-8
MF:C19H17NO4
MW:323.34
EINECS:
Product Categories:
Mol File:2411741-01-8.mol
4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- Structure
4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- Chemical Properties
Boiling point 565.4±50.0 °C(Predicted)
density 1.424±0.06 g/cm3(Predicted)
pka8.88±0.40(Predicted)
Safety Information
MSDS Information
4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- Usage And Synthesis
UsesAntituberculosis agent-2 (Compound 8d) is an antituberculosis agent against agent-sensitive and multidrug-resistant tuberculosis. Antituberculosis agent-2 shows anti-tuberculosis activity with MIC values of 0.454, 1.757 and 1.644 μg/mL against M. tuberculosis H37Rv, 13946 and 14862, respectively. Antituberculosis agent-2 displays favorable mouse and human microsomal stability, low cytotoxicity, and acceptable oral bioavailability[1].
References[1] Zhao W, et al. Design, synthesis, and biological evaluation of novel 4H-chromen-4-one derivatives as antituberculosis agents against multidrug-resistant tuberculosis. Eur J Med Chem. 2020 Mar 1;189:112075. DOI:10.1016/j.ejmech.2020.112075
4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)- Preparation Products And Raw materials
Tag:4H-1-Benzopyran-4-one, 5-(1-azetidinylmethyl)-6-hydroxy-2-(4-hydroxyphenyl)-(2411741-01-8) Related Product Information
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