Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]-

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Company Name: Tianjin Kailiqi Biotechnology Co., Ltd.  
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Email: klq@cw-bio.com
Company Name: TargetMol Chemicals Inc.  
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Company Name: TargetMol Chemicals Inc.  
Tel: 13564774135
Email: marketing@targetmol.com

Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- manufacturers

  • CB1/2 agonist 4
  • CB1/2 agonist 4 pictures
  • $2785.00
  • 2026-04-20
  • CAS:2772949-38-7
  • Purity:
  • Supply Ability: 10g
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- Basic information
Product Name:Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]-
Synonyms:Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]-;CB1/2 agonist 4
CAS:2772949-38-7
MF:C27H45NO3
MW:431.65
EINECS:
Product Categories:
Mol File:2772949-38-7.mol
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- Structure
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- Chemical Properties
Boiling point 586.2±50.0 °C(Predicted)
density 1.00±0.1 g/cm3(Predicted)
pka16.22±0.20(Predicted)
Safety Information
MSDS Information
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- Usage And Synthesis
UsesCB1/2 agonist 4 is a full CB1 agonist and CB2 partial agonist with EC50 values of 15.09 nM and 1.16 nM, respectively. CB1/2 agonist 4 also has hCB1 and hCB2 receptor affinities with Ki values of 1.1 nM and 4.2 nM, respectively. CB1/2 agonist 4 has a significant antinociceptive activity, and also can activate cannabinoid and TRPV1 receptor with values of IC50 and EC50 is 0.8 μM and 0.12 μM, respectively[1].
in vivo

CB1/2 agonist 4 (compound 24) (1, 3 and 4 mg/kg, i.p.) has a stronger antinociceptive activity[1].
CB1/2 agonist 4 (1, 3 and 4 mg/kg, i.p.) can activate TRPV1 channel and it behaved as a good TRPV1 agonist with an IC50 value of 0.8 μM and EC50 value of 0.12 μM[1].

Animal Model:Male CD-1 outbred mice[1]
Dosage:1, 3 and 4 mg/kg
Administration:1, 3 and 4 mg/kg, i.p.
Result:Significantly reduced the late phase of formalin-induced nociceptive behaviour in a dose dependent manner and slightly decreased also the first phase of nociceptive response.
References[1] Antonella Brizzi, et al. Synthetic bioactive olivetol-related amides: The influence of the phenolic group in cannabinoid receptor activity. Bioorg Med Chem. 2020 Jun 1;28(11):115513. DOI:10.1016/j.bmc.2020.115513
Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]- Preparation Products And Raw materials
Tag:Octanamide, N-cyclopropyl-8-[3-(1,1-dimethylheptyl)-5-methoxyphenoxy]-(2772949-38-7) Related Product Information
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