| Company Name: |
Bide Pharmatech Ltd.
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| Tel: |
400-1647117 13681763483 |
| Email: |
product02@bidepharm.com |
| Products Intro: |
Product Name:MAO-B-IN-9
CAS:2416910-88-6
Purity:98% Package:10mg;25mg;50mg;100mg Remarks:BD01580597
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| | MAO-B-IN-9, 10 mM in DMSO Basic information |
| | MAO-B-IN-9, 10 mM in DMSO Chemical Properties |
| Boiling point | 377.3±42.0 °C(Predicted) | | density | 1.10±0.1 g/cm3(Predicted) | | pka | 13.55±0.70(Predicted) | | form | Solid | | color | White to off-white |
| | MAO-B-IN-9, 10 mM in DMSO Usage And Synthesis |
| Uses | MAO-B-IN-9 (compound 16) is a potent, selective, BBB-penetrated, irreversible and time-dependent MAO-B (monoamine oxidase B) inhibitor, with an IC50 of 0.18 μM. MAO-B-IN-9 prevents Aβ1-42-induced neuronal cell death. MAO-B-IN-9 shows neuroprotective effects, which may be the result of its Aβ1-42 anti-aggregation effects[1]. MAO-B-IN-9 is a click chemistry reagent, itcontains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. | | IC 50 | MAO-B: 0.178 ± 0. μM (IC50) | | References | [1] Koak U, et al. N-alkylpiperidine carbamates as potential anti-Alzheimer's agents. Eur J Med Chem. 2020 Jul 1;197:112282. DOI:10.1016/j.ejmech.2020.112282 |
| | MAO-B-IN-9, 10 mM in DMSO Preparation Products And Raw materials |
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