2-Thiazolamine, N-[1,1'-biphenyl]-4-yl-4-imidazo[1,2-a]pyrimidin-3-yl- manufacturers
- EV-A71-IN-1
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- $1520.00
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2026-04-21
- CAS:2413648-96-9
- Purity:
- Supply Ability: 10g
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| | 2-Thiazolamine, N-[1,1'-biphenyl]-4-yl-4-imidazo[1,2-a]pyrimidin-3-yl- Basic information |
| | 2-Thiazolamine, N-[1,1'-biphenyl]-4-yl-4-imidazo[1,2-a]pyrimidin-3-yl- Chemical Properties |
| density | 1.35±0.1 g/cm3(Predicted) | | pka | 2.79±0.30(Predicted) |
| | 2-Thiazolamine, N-[1,1'-biphenyl]-4-yl-4-imidazo[1,2-a]pyrimidin-3-yl- Usage And Synthesis |
| Uses | EV-A71-IN-1 is a human enterovirus A71 (EV-A71) capsid protein inhibitor with an EC50 of 0.27 μM against EV-A71. EV-A71-IN-1 is a capsid binder that blocks the interaction between the viral VP1 and the host receptor hSCARB2. EV-A71-IN-1 inhibits a series of different human enteroviruses without significant cytotoxicity (CC50>56.2 μM)[1]. | | References | [1] Xu Z, et al. Discovery of aminothiazole derivatives as novel human enterovirus A71 capsid protein inhibitors. Bioorg Chem. 2022;122:105683. DOI:10.1016/j.bioorg.2022.105683 |
| | 2-Thiazolamine, N-[1,1'-biphenyl]-4-yl-4-imidazo[1,2-a]pyrimidin-3-yl- Preparation Products And Raw materials |
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