| Company Name: |
Energy Chemical |
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021-58432009 400-005-6266 |
| Email: |
marketing@energy-chemical.com |
myxochelin A manufacturers
- Myxochelin A
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- $960.00
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2026-05-11
- CAS:120243-02-9
- Purity:
- Supply Ability: 10g
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| | myxochelin A Basic information |
| Product Name: | myxochelin A | | Synonyms: | myxochelin A;Benzamide, N,N'-[(1S)-1-(hydroxymethyl)-1,5-pentanediyl]bis[2,3-dihydroxy- | | CAS: | 120243-02-9 | | MF: | C20H24N2O7 | | MW: | 404.41 | | EINECS: | | | Product Categories: | | | Mol File: | 120243-02-9.mol |  |
| | myxochelin A Chemical Properties |
| storage temp. | Store at -20°C | | solubility | DMSO: soluble,Ethanol: soluble,Methanol: soluble | | form | A solid |
| | myxochelin A Usage And Synthesis |
| Description | Myxochelin A is a microbial metabolite that has been found in A. disciformis and has diverse biological activities. It is active against Gram-positive bacteria, including B. cereus, S. aureus, and M. luteus, but not Gram-negative bacteria or fungi in an agar diffusion assay when used at a concentration of 80 μg/disc. Myxochelin A inhibits 5-lipoxygenase (5-LO) activity with an IC50 value of 1.9 μM for the recombinant human enzyme. It is cytotoxic to 26-L5 colon cancer cells when used at a concentration of 3 μg/ml. | | Uses | Myxochelin A is a potent inhibitor of human 5-lipoxygenase (5-LO). Studies show that Myxochelin A is a natural product that may possess potent antitumor activity at non-cytotoxic concentrations. | | References | [1] B KUNZE. Myxochelin A, a new iron-chelating compound from Angiococcus disciformis (Myxobacterales). Production, isolation, physico-chemical and biological properties.[J]. Journal of Antibiotics, 1989, 42 1: 14-17. DOI: 10.7164/antibiotics.42.14
[2] SEBASTIAN SCHIEFERDECKER. Myxochelins Target Human 5-Lipoxygenase[J]. Journal of Natural Products , 2015, 78 2: 335-338. DOI: 10.1021/np500909b
[3] SATOSHI MIYANAGA. Absolute Configuration and Antitumor Activity of Myxochelin A Produced by Nonomuraea pusilla TP-A0861[J]. Journal of Antibiotics, 2006, 59 11: 698-703. DOI: 10.1038/ja.2006.93 |
| | myxochelin A Preparation Products And Raw materials |
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