- 3-Hydroxypivalic acid
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- $100.00 / 1KG
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2025-05-26
- CAS:4835-90-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 10000kg
- 3-Hydroxypivalic acid
-
- $1.00 / 1KG
-
2019-07-06
- CAS:4835-90-9
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
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| | 3-Hydroxypivalic acid Basic information |
| Product Name: | 3-Hydroxypivalic acid | | Synonyms: | THYODIGLYCOL;THIODIETHYLENE GLYCOL;3-hydroxy-2,2-dimethyl-propanoicaci;Propanoic acid, 3-hydroxy-2,2-dimethyl-;HYDROXYPIVALIC ACID;BETA-THIODIGLYCOL;3-Hydroxypivalic acid;2,2-DIMETHYL-3-HYDROXYPROPANOIC ACID | | CAS: | 4835-90-9 | | MF: | C5H10O3 | | MW: | 118.13 | | EINECS: | 225-419-8 | | Product Categories: | | | Mol File: | 4835-90-9.mol |  |
| | 3-Hydroxypivalic acid Chemical Properties |
| Melting point | −16 °C(lit.) | | Boiling point | 164-166 °C20 mm Hg(lit.) | | density | 1.221 g/mL at 25 °C(lit.) | | vapor pressure | 0.446Pa at 25℃ | | refractive index | n20/D 1.5215(lit.) | | Fp | >230 °F | | storage temp. | Sealed in dry,Room Temperature | | solubility | Chloroform (Sparingly, Heated), Methanol (Slightly) | | pka | 4.55±0.10(Predicted) | | form | powder to crystal | | color | White to Almost white | | Water Solubility | Soluble in water. | | BRN | 1747025 | | LogP | -0.02 | | CAS DataBase Reference | 4835-90-9(CAS DataBase Reference) | | NIST Chemistry Reference | Hydroxy pivalic acid(4835-90-9) | | EPA Substance Registry System | Hydroxypivalic acid (4835-90-9) |
| Hazard Codes | Xi | | Risk Statements | 36-41-37/38 | | Safety Statements | 26-37/39 | | WGK Germany | 1 | | RTECS | KM2975000 | | F | 3-13-23 | | TSCA | TSCA listed | | HS Code | 2918.19.9000 |
| | 3-Hydroxypivalic acid Usage And Synthesis |
| Chemical Properties | white crystal | | Uses | 3-Hydroxy-2,2-dimethylpropionic acid is used as pharmaceutical intermediate. | | Reactions | When 3-Hydroxypivalic acid (1r)
was used under standard conditions, the free hydroxyl group was
well tolerated and after conjugated addition, the lactonization took
place smoothly to afford compound 3ra as a single
diastereoisomer (according to 1H- and 13C-NMR)[1].
Tandem decarboxylation-Giese reaction-lactonization
| | Flammability and Explosibility | Not classified | | References | [1] NIEVES P. RAMIREZ; Jose C G G. Decarboxylative Giese-Type Reaction of Carboxylic Acids Promoted by Visible Light: A Sustainable and Photoredox-Neutral Protocol[J]. European Journal of Organic Chemistry, 2017. DOI:10.1002/ejoc.201601478. |
| | 3-Hydroxypivalic acid Preparation Products And Raw materials |
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