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| | C18 dihydro Ceramide-d3 (d18:0/18:0-d3) Basic information |
| | C18 dihydro Ceramide-d3 (d18:0/18:0-d3) Chemical Properties |
| Boiling point | 694.822±45.00 °C(Press: 760.00 Torr)(predicted) | | density | 0.910±0.06 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | solubility | DMSO: 0.5 mg/ml | | pka | 14.303±0.20(predicted) |
| | C18 dihydro Ceramide-d3 (d18:0/18:0-d3) Usage And Synthesis |
| Uses | C18 Dihydroceramide-d3-1 (N-octadecaoyl-D-eytho-Dihydosphigosie-d3) is deuterium labeled C18 Dihydroceramide. C18 Dihydroceramide is an ester product[1]. | | References | [1] Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. DOI:10.1177/1060028018797110
[2] AH YOUNG LEE . Dihydroceramide is a key metabolite that regulates autophagy and promotes fibrosis in hepatic steatosis model[J]. Biochemical and biophysical research communications, 2017, 494 3: Pages 460-469. DOI: 10.1016/j.bbrc.2017.10.110
[3] LEONORE WIGGER. Plasma Dihydroceramides Are Diabetes Susceptibility Biomarker Candidates in Mice and Humans.[J]. Cell reports, 2017, 18 9: 2269-2279. DOI: 10.1016/j.celrep.2017.02.019
[4] KYUNG-MI JOO . Relationship of ceramide–, and free fatty acid–cholesterol ratios in the stratum corneum with skin barrier function of normal, atopic dermatitis lesional and non-lesional skins[J]. Journal of dermatological science, 2015, 77 1: Pages 71-74. DOI: 10.1016/j.jdermsci.2014.10.001 |
| | C18 dihydro Ceramide-d3 (d18:0/18:0-d3) Preparation Products And Raw materials |
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