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| | butyryl timolol Basic information |
| Product Name: | butyryl timolol | | Synonyms: | butyryl timolol;O-Butyryltimolol;BUTYRYLTIMOLOL; BUTYRYL TIMOLOL; BUTYRYL-TIMOLOL;Butanoic acid, 1-[[(1,1-dimethylethyl)amino]methyl]-2-[[4-(4-morpholinyl)-1,2,5-thiadiazol-3-yl]oxy]ethyl ester, (S)- (9CI) | | CAS: | 106351-79-5 | | MF: | C17H30N4O4S | | MW: | 386.51 | | EINECS: | | | Product Categories: | | | Mol File: | 106351-79-5.mol |  |
| | butyryl timolol Chemical Properties |
| Boiling point | 511.5±50.0 °C(Predicted) | | density | 1.169±0.06 g/cm3(Predicted) | | storage temp. | Store at -20°C | | pka | 8.74±0.10(Predicted) | | form | Liquid | | color | Colorless to light yellow |
| | butyryl timolol Usage And Synthesis |
| Uses | Butyryltimolol, an effective precursor of Timolol, improves the corneal penetration of Timolol[1]. Butyryltimolol is a β-adrenergic blocker[2]. | | IC 50 | β adrenergic receptor | | References | [1] Chang SC, et al. Relative effectiveness of prodrug and viscous solution approaches in maximizing the ratio of ocular to systemic absorption of topically applied timolol. Exp Eye Res. 1988 Jan;46(1):59-69. DOI:10.1016/s0014-4835(88)80093-9
[2] Potter DE, et al. Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol. Curr Eye Res. 1988 Aug;7(8):755-9. DOI:10.3109/02713688809033206 |
| | butyryl timolol Preparation Products And Raw materials |
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