| Company Name: |
TargetMol Chemicals Inc.
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| Tel: |
15002134094 |
| Email: |
marketing@targetmol.cn |
| Products Intro: |
Product Name:AQIM-I
CAS:2247881-73-6
Package:10mg;50mg
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| Product Name: | AQIM-I | | Synonyms: | AQIM-I;1H-Anthra[2,3-d]imidazolium, 1,3-dimethyl-4,11-dioxo-, iodide (1:1) | | CAS: | 2247881-73-6 | | MF: | C17H13N2O2.I | | MW: | 404.2 | | EINECS: | | | Product Categories: | | | Mol File: | 2247881-73-6.mol |  |
| | AQIM-I Chemical Properties |
| | AQIM-I Usage And Synthesis |
| Uses | AQIM-I is an inhibitor of survivin via inhibits survivin expression and colony formation. AQIM-I induces ROS production, apoptosis, cell cycle arrest, DNA damage, and autophagy. AQIM-I inhibits nonsmall cell lung cancer cells A549 with an IC50 value of 9 nM[1]. | | References | [1] Jing Yuan, et al. Pioneering 4,11-Dioxo-4,11-dihydro-1 H-anthra[2,3- d]imidazol-3-ium Compounds as Promising Survivin Inhibitors by Targeting ILF3/NF110 for Cancer Therapy. J Med Chem. 2023. DOI:10.1021/acs.jmedchem.3c01551 |
| | AQIM-I Preparation Products And Raw materials |
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