TEAD-IN-10

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TEAD-IN-10 Suppliers list
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Email: marketing@targetmol.cn
TEAD-IN-10 Basic information
Product Name:TEAD-IN-10
Synonyms:TEAD-IN-10;2-Propen-1-one, 1-[3-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1-azetidinyl]-
CAS:3032196-65-6
MF:C15H14F3NO
MW:281.27
EINECS:
Product Categories:
Mol File:3032196-65-6.mol
TEAD-IN-10 Structure
TEAD-IN-10 Chemical Properties
Boiling point 387.0±42.0 °C(predicted)
density 1.299±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
pka-1.68±0.40(predicted)
Safety Information
MSDS Information
TEAD-IN-10 Usage And Synthesis
UsesTEAD-IN-10 (compound 15) has good selective activity and inhibitory effect on TEAD1 (IC50=14 nM), TEAD2 (IC50=179 nM) and TEAD3 (IC50=4 nnM) as a covalent inhibitor. TEAD-IN-10 can be used for cancer research[1].
IC 50TAED1: 14 nM (IC50); TAED2: 179 nM (IC50); TAED3: 4 nM (IC50)
References[1] Henry William, et al. Yap/taz-tead oncoproteins inhibitors.WO2024059317A1.2023-09-15
TEAD-IN-10 Preparation Products And Raw materials
Tag:TEAD-IN-10(3032196-65-6) Related Product Information
Pyrazolo[1,5-a]pyrimidin-7(4H)-one, 5-(4-cyclohexylphenyl)-3-[[3-(fluoromethyl)-1-azetidinyl]carbonyl]-2-(3-methyl-2-pyrazinyl)- IAG933 CYTOCHALASIN D 2-Propenamide, N-[3-(4-chlorophenoxy)-4-methylphenyl]- 2-Propen-1-one, 1-[(3R,4R)-3-[4-(3-pyridinyl)-1H-1,2,3-triazol-1-yl]-4-[[4-(trifluoromethyl)phenyl]methoxy]-1-pyrrolidinyl]- 2-Naphthalenecarboxamide, N-[(1S)-1-(6-amino-2-pyridinyl)ethyl]-5-[4-(trifluoromethyl)phenyl]-